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Using NeuroRPM to evaluate a DBS programming adjustment

USE CASE: DBS PROGRAMMING EVALUATION

NeuroRPM provides AI-enabled Parkinson's monitoring that helps clinicians understand how symptom control changes after a DBS programming adjustment in daily life.

A real-world clinical example

See how NeuroRPM data helped compare symptom patterns before and after a deep brain
stimulation (DBS) programming adjustment, identify changes in motor control, and support a
more informed programming review.

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NeuroRPM monitoring

A Parkinson’s patient underwent a DBS programming adjustment while the medication regimen remained unchanged. The care team used NeuroRPM to evaluate how the programming adjustment affected real-world symptom control.

2

Programming comparison

The clinician used NeuroRPM to compare symptom patterns before and after the DBS programming adjustment. NeuroRPM tracked ON time, tremor, bradykinesia, and dyskinesia across daily cycles and around medication dose windows.

3

Data reveals insights

NeuroRPM showed that the period after the DBS programming adjustment was associated with higher ON time, lower OFF time, reduced bradykinesia, very low tremor prevalence, and reduced dyskinesia overall. The most notable improvements were observed in late evening ON time and in morning and late evening bradykinesia.

4

Programming review

These insights gave the clinician objective data to evaluate the impact of the DBS programming adjustment, assess changes in daily motor stability, and identify time periods where additional programming review or follow-up monitoring may be useful.

NeuroRPM report highlights

DBS Programming Comparison

NeuroRPM compared real-world symptom patterns before and after a DBS programming adjustment, with no medication change, showing how symptom control changed overall, across symptom categories, and across the patient’s typical day.

ON Time

 +4.5%

Tremor Detected

Bradykinesia Detected

-0.6%

-2.6%

Dyskinesia Detected

-1.3%

Overall Symptom Comparison

Prior plan

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Prior plan monitored

Adaptive plan monitored

Medication

662.1 hrs

651.5 hrs

unchanged

Time-of-Day Bradykinesia Prevalence

Prior plan

Adaptive plan

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Prior plan prevalence

9.3%

Adaptive plan prevalence

6.7%

Overall change

2.6%

vs. prior plan

Key insight

NeuroRPM detected improved motor stability after the DBS programming adjustment. ON state increased while bradykinesia, tremor, and dyskinesia decreased overall. The clearest gains were seen in late evening ON time and in morning and late evening bradykinesia, helping the clinician identify when programming delivered the most benefit. These data can also help clinicians evaluate whether medication timing or dose adjustments may be appropriate as DBS therapy is titrated.

Clinical impact

Clarifies programming response

Shows how real-world symptom patterns changed after a DBS programming adjustment, including ON time, OFF time, bradykinesia, tremor, and dyskinesia.

Separates DBS impact from medication change

Helps clinicians understand how symptom control changes as DBS settings are adjusted, while also providing real-world data that may support later medication timing or dose adjustments as the patient moves toward a stable balance between DBS therapy and medication.

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Supports DBS programming review

Provides objective data to help clinicians evaluate whether programming settings are associated with improved daily motor control, reduced dyskinesia, improved ON time, and where additional review may be needed.

Tracks impact over time

Enables comparison of prior and current DBS programming periods to evaluate whether symptom control improved, worsened, or changed across specific parts of the day.

Transform DBS care with data-driven insight

NeuroRPM helps clinicians evaluate how symptom control changes after DBS programming adjustments. By combining AI-enabled Parkinson’s monitoring with real-world symptom tracking, NeuroRPM gives care teams objective data to review programming response, support follow-up decisions, and better understand motor patterns across daily life.

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